Star Trek: The Role-Playing Game Box Set contains a 128-page basic rule book, a 50-plus page adventure book containing three adventures, a 22-inch by 33-inch black hex map for starship combat, pages of deck plans, over 100 color counters, and two 20-sided percentile dice.

The books provide information about character races, skills, combat, equipment, weapons, medicine, and various statistics.

The game books also feature photos and illustrations depicting the original 1960s television show along with game statistics for the many of the popular television characters from Kirk and Spock to more obscure characters such as Riley, DeSalle, Kyle, Sarek, Cyrano Jones, Harry Mudd, and Khan Noonian Singh.