Splicers is a new science fiction role-playing game set on a devastated world where machines rule, and human beings are vermin who are hunted and exterminated. The human struggle is complicated by a nano-virus that instantly turns metal objects touched by human flesh into killing machines. Consequently, humans have been forced to turn to organic technology to battle the world-dominating machines if they hope to reclaim any portion of their planet back for themselves. The human resistance, their genetically spliced weapons and power armor, secret cities and plans to retake their world. The machine mind that rules from on high and commands its robot legions like a psychotic general. The nano-plague and its ramifications. Human O.C.C.s, strongholds and world background. A new, stand-alone role-playing game heavy on science fiction. Mega-Damage system "“ compatible with Rifts , Chaos Earth , and Phase World .